Search on: RIBOSOME INACTIVATING PROTEINS 
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Descriptor English:   Ribosome Inactivating Proteins 
Descriptor Spanish:   Proteínas Inactivadoras de Ribosomas 
Descriptor Portuguese:   Proteínas Inativadoras de Ribossomos 
Synonyms English:   Polynucleotide Adenosine Glycosidase
RIP (Ribosome Inactivating Proteins)
RNA Glycosylase
rRNA N-Glycosylases
Adenosine Glycosidase, Polynucleotide
Glycosidase, Polynucleotide Adenosine
Glycosylase, RNA
Inactivating Proteins, Ribosome
N-Glycosidase, RNA
N-Glycosylases, rRNA
Proteins, Ribosome Inactivating
RNA N Glycosidase
rRNA N Glycosylases
RNA N-Glycosidase  
Tree Number:   D08.811.277.450.430.700
D12.776.765.710
Definition English:   N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity. 
Pharmacological Action:   Protein Synthesis Inhibitors
 
History Note English:   2008(1988) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52713 
Unique Identifier:   D054788 

Occurrence in VHL:
 

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